Well Referenced

Tag: occupational health

CaNa2EDTA chelation attenuates cell damage in workers exposed to lead–a pilot study

This 2015 pilot study investigated the effects of CaNa₂EDTA chelation therapy on oxidative and genotoxic damage in smelting factory workers with chronic lead exposure averaging 5.8 ± 1.2 years. Following a five-day CaNa₂EDTA regimen, significant reductions were observed in oxidative stress biomarkers, including normalized activities of antioxidant enzymes (Cu,Zn-SOD and

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June 26, 2025 No Comments

Recommendations for Medical Management of Adult Lead Exposure

This guideline outlines evidence-based recommendations for managing adult lead exposure, emphasizing that adverse health effects can occur at blood lead levels (BLLs) below 40 μg/dL. Key recommendations include: removing individuals from occupational lead exposure if a single BLL exceeds 30 μg/dL or if two consecutive BLLs measured over a 4-week

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June 26, 2025 No Comments

Cadmium Toxicity and Treatment

This comprehensive review examines cadmium, a highly toxic heavy metal with widespread environmental and occupational exposure. Cadmium accumulates in the body, particularly in the kidneys and liver, leading to multi-organ damage. Chronic exposure is associated with renal dysfunction, bone demineralization, and increased cancer risk. The primary sources of cadmium exposure

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June 26, 2025 No Comments

Molecular effects of ozone on amino acids and proteins, especially human hemoglobin and albumin, and the need to personalize ozone concentration in major ozone autohemotherapy

This retrospective controlled cohort study evaluated intravenous (IV) ozonized saline therapy as a prophylactic intervention for healthcare workers (HCWs) in a COVID-19 hospital in India. Among 235 HCWs, 64 received ozone therapy in addition to standard prophylaxis, while 171 received standard prophylaxis only. The incidence of COVID-19 was significantly lower

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June 26, 2025 No Comments

The administration of N-acetylcysteine reduces oxidative stress and regulates glutathione metabolism in the blood cells of workers exposed to lead

This randomized controlled trial investigated the effects of N-acetylcysteine (NAC) supplementation on oxidative stress and glutathione metabolism in 171 lead-exposed male workers. Participants were divided into four groups: a control group and three groups receiving NAC at doses of 200 mg, 400 mg, or 800 mg per day for 12

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June 26, 2025 No Comments