Safety and efficacy of alpha-lipoic acid oral supplementation in the reduction of pain with unknown etiology: A monocentric, randomized, double-blind, placebo-controlled clinical trial
This 2021 monocentric, randomized, double-blind, placebo-controlled clinical trial published in Biomedicine & Pharmacotherapy (DOI: 10.1016/j.biopha.2021.112308, PMID: 34649217) evaluated the safety and efficacy of alpha-lipoic acid (ALA) supplementation for reducing chronic pain of unknown etiology. Involving 100 adult participants over 60 days, the study found that ALA significantly reduced pain intensity
June 26, 2025
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