Tag: non-invasive biomarker

Methylated circulating tumor DNA in blood: power in cancer prognosis and response

This 2016 review explores the role of methylated circulating tumor DNA (ctDNA) as a non-invasive biomarker in cancer prognosis and treatment monitoring. ctDNA, detectable in plasma or serum, reflects tumor-specific genetic and epigenetic alterations, including aberrant DNA methylation patterns. These methylation changes are often consistent across patients, making them reliable

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Utility of faecal calprotectin analysis in adult inflammatory bowel disease

This study explores the use of faecal calprotectin (FC) measurement as a non-invasive biomarker for diagnosing and managing inflammatory bowel disease (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC). Elevated FC levels correlate with active disease and can help distinguish IBD from other gastrointestinal conditions like irritable bowel syndrome

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