Well Referenced

Tag: neurotransmitter systems

Influence of dopaminergic, adrenergic and cholinergic blockade and TRH administration on GH responses to GRF 1-29

This study investigated the effects of dopaminergic, adrenergic, and cholinergic blockade, along with TRH administration, on growth hormone (GH) responses to growth hormone-releasing factor (GRF) 1-29. It was found that these neurotransmitter systems modulate GH secretion in response to GRF, and TRH administration also influenced GH release. The study highlights

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June 26, 2025 No Comments

Emerging evidence for the antidepressant effect of cannabidiol and the underlying molecular mechanisms

This review examines preclinical studies on cannabidiol (CBD) and its potential antidepressant effects, focusing on molecular mechanisms and interactions with neurotransmitter systems such as serotonergic, glutamatergic, and endocannabinoid pathways. CBD has been shown to enhance brain-derived neurotrophic factor (BDNF) signaling, promote synaptogenesis in the medial prefrontal cortex, and support neurogenesis

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June 26, 2025 No Comments

Methylene blue and Alzheimer’s disease

This review discusses the potential of methylene blue (MB) as a therapeutic agent for Alzheimer’s disease (AD). MB has been shown to reduce amyloid plaque and neurofibrillary tangle formation, improve mitochondrial function, and modulate neurotransmitter systems, including cholinergic, serotonergic, and glutamatergic pathways. These combined effects suggest that MB could offer

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June 26, 2025 No Comments