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Tag: neuroprotective therapy

Coenzyme Q10 deficiency in patients with Parkinson’s disease

This study examined coenzyme Q10 (CoQ10) deficiency in Parkinson’s disease (PD) patients compared to age- and gender-matched controls, revealing a significantly higher prevalence of CoQ10 deficiency in PD patients (32-36%) versus controls (8-9%), with odds ratios ranging from 4.7 to 5.4 (p=0.0012-0.006). CoQ10 plays a crucial role in mitochondrial function

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June 26, 2025 No Comments

Methylene Blue Improves Brain Mitochondrial ABAD Functions and Decreases Aβ in a Neuroinflammatory Alzheimer’s Disease Mouse Model

This study investigates the effects of methylene blue (MB) in a mouse model of Alzheimer’s disease (AD) induced by neuroinflammation. The study found that MB treatment reduced amyloid beta (Aβ) oligomers, decreased oxidative stress, and improved mitochondrial function by inhibiting the mitochondrial enzyme ABAD. Additionally, MB treatment restored brain estradiol

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June 26, 2025 No Comments