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Tag: neuroimmune disorders

The glutathione system: a new drug target in neuroimmune disorders

This 2014 review discusses the glutathione (GSH) system as a critical regulator of redox homeostasis, immune function, and mitochondrial integrity in neuroimmune disorders. GSH depletion is associated with increased oxidative and nitrosative stress, which can impair neural and immune functions, contributing to diseases such as depression, chronic fatigue syndrome, and

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June 26, 2025 No Comments

Recognizing the Leaky Gut as a Trans-diagnostic Target for Neuroimmune Disorders Using Clinical Chemistry and Molecular Immunology Assays

This 2018 systematic review published in Current Topics in Medicinal Chemistry (PMID: 30430944) examines the role of increased intestinal permeability—commonly referred to as leaky gut—in the development of neuroimmune disorders such as major depressive disorder (MDD), chronic fatigue syndrome (CFS), schizophrenia, and irritable bowel syndrome (IBS). The review highlights a

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June 26, 2025 No Comments