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Tag: neurodegenerative disorders

From Mitochondrial Function to Neuroprotection-an Emerging Role for Methylene Blue

This review explores the potential neuroprotective role of methylene blue (MB), particularly its ability to enhance mitochondrial function in neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease, stroke, and traumatic brain injury. MB acts as an alternative electron carrier in the mitochondrial electron transport chain, improving ATP production and reducing

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June 26, 2025 No Comments

Potential application of the oxidative nucleic acid damage biomarkers in detection of diseases

This review explores the role of oxidative nucleic acid damage biomarkers, specifically 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG) and 8-oxo-7,8-dihydroguanosine (8-oxoG), in disease detection and drug development. Elevated levels of these biomarkers, found at 1.3 to 5 times higher in patients than controls, have been linked to various diseases, including cancer, neurodegenerative disorders, and

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June 26, 2025 No Comments