Agonists of growth hormone-releasing hormone stimulate self-renewal of cardiac stem cells
This study explores the potential therapeutic benefits of growth hormone-releasing hormone (GHRH) receptor agonists for cardiac stem cells (CSCs) in heart failure treatment. GHRH-R agonists like JI-38, MR-356, and MR-409 were shown to stimulate CSC proliferation and survival, particularly under oxidative stress, by activating key cell signaling pathways (ERK and
June 26, 2025
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