This 1988 review article examines the prevalence and mechanisms of weight gain associated with tricyclic antidepressants (TCAs), monoamine oxidase inhibitors (MAOIs), and lithium therapy. TCAs are linked to appetite stimulation, carbohydrate cravings, and a dose-dependent weight gain ranging from 0.57 to 1.37 kg per month, potentially due to noradrenergic or
This article reviews the neuroprotective effects of monoamine oxidase inhibitors (MAOIs), such as selegiline and rasagiline, in the context of age-dependent neurodegenerative disorders like Parkinson’s and Alzheimer’s diseases. The review highlights that MAOIs work by reducing oxidative stress, stabilizing mitochondria, enhancing neurotrophic factors like nerve growth factor (NGF) and brain-derived
This in vitro study examined the inhibitory effects of five structural analogues of methylene blue (MB)—neutral red, Nile blue, new methylene blue, cresyl violet, and 1,9-dimethyl methylene blue—on human monoamine oxidase (MAO) enzymes. The results demonstrated that all analogues selectively inhibited the MAO-A isoform, with cresyl violet (IC₅₀ = 0.0037
