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Tag: MnSOD

Estrogen Replacement Therapy Induces Antioxidant and Longevity-Related Genes in Women after Medically Induced Menopause

This 2021 clinical study investigated the effects of estrogen replacement therapy (ERT) on antioxidant and longevity-related gene expression in 16 women aged 18–42 undergoing medically induced menopause as part of fertility treatment. Blood samples were collected at four stages: baseline, post-menopause induction, after estrogen therapy, and after combined estrogen-progesterone therapy.

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June 26, 2025 No Comments

Resveratrol interacts with estrogen receptor-β to inhibit cell replicative growth and enhance stress resistance by upregulating mitochondrial superoxide dismutase

This study explored how resveratrol interacts with estrogen receptor-β (ER-β) to upregulate mitochondrial superoxide dismutase (MnSOD), leading to inhibited cell growth and enhanced resistance to oxidative stress. The effects were observed across multiple cell lines, including human lung fibroblasts, mouse myoblasts, and human neuroblastoma cells. The study found that the

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June 26, 2025 No Comments