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Tag: MitoQ

Chronic Supplementation With a Mitochondrial Antioxidant (MitoQ) Improves Vascular Function in Healthy Older Adults

This randomized, double-blind, placebo-controlled crossover trial examined the impact of 6 weeks of MitoQ (20 mg/day) supplementation on vascular function in 20 healthy older adults aged 60–79 years with baseline endothelial dysfunction. MitoQ significantly enhanced brachial artery flow-mediated dilation (FMD) by 42% relative to placebo, indicating improved endothelial function. Among

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June 26, 2025 No Comments

Oxidative stress and mitochondrial dysfunction across broad-ranging pathologies: toward mitochondria-targeted clinical strategies

This systematic review examines the role of oxidative stress and mitochondrial dysfunction in a wide range of chronic diseases, including neurodegenerative disorders, cardiovascular disease, metabolic syndrome, cancer, and age-related conditions. The review underscores the damaging cycle of reactive oxygen species (ROS) and mitochondrial impairment, which drives cellular decline. It highlights

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June 26, 2025 No Comments