Tag: mitochondrial therapy

Mitochondrial Dysfunction as an Underlying Cause of Skeletal Muscle Disorders

This systematic review discusses how mitochondrial dysfunction is a primary contributor to skeletal muscle disorders, driven by impaired oxidative phosphorylation, mtDNA mutations, calcium imbalance, defective mitophagy, and abnormalities in mitochondrial dynamics. These disruptions lead to decreased energy production, muscle degeneration, and cellular stress. The review emphasizes the need for targeted

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Advances in metal-induced oxidative stress and human disease

This article proposes a hybrid orthomolecular protocol aimed at cancer treatment, focusing on targeting mitochondrial dysfunction in cancer cells. It combines traditional cancer therapies with mitochondrial-targeted treatments, such as antioxidants, to disrupt the altered energy metabolism of cancer cells and improve therapy effectiveness. In vitro and animal studies suggest that

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