Tag: mitochondrial antioxidants

Resveratrol interacts with estrogen receptor-β to inhibit cell replicative growth and enhance stress resistance by upregulating mitochondrial superoxide dismutase

This study explored how resveratrol interacts with estrogen receptor-β (ER-β) to upregulate mitochondrial superoxide dismutase (MnSOD), leading to inhibited cell growth and enhanced resistance to oxidative stress. The effects were observed across multiple cell lines, including human lung fibroblasts, mouse myoblasts, and human neuroblastoma cells. The study found that the

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Maintaining good hearing: calorie restriction, Sirt3, and glutathione

This review examines how calorie restriction (CR) can slow the progression of age-related hearing loss (AHL), a common aging condition linked to the degeneration of sensory hair cells, spiral ganglion neurons, and the stria vascularis in the cochlea. The study highlights mitochondrial Sirt3, a sirtuin protein, as a critical mediator

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