methyl donors Archives - Well Referenced

Choline’s role in maintaining liver function: new evidence for epigenetic mechanisms

This article reviews the crucial role of choline in maintaining liver function, focusing on how choline influences gene expression through epigenetic mechanisms like DNA and histone methylation. Choline is vital for generating S-adenosylmethionine, which regulates liver-related gene expression. A deficiency in choline can lead to liver issues such as fatty

June 26, 2025 No Comments

Betaine attenuates hepatic steatosis by reducing methylation of the MTTP promoter and elevating genomic methylation in mice fed a high-fat diet

This study examined the effects of betaine supplementation on hepatic steatosis in mice fed a high-fat diet, with a focus on epigenetic mechanisms. Betaine was found to improve liver function by reducing methylation of the microsomal triglyceride transfer protein (MTTP) promoter, leading to increased MTTP expression, which plays a crucial

June 26, 2025 No Comments

Tag: methyl donors

Choline’s role in maintaining liver function: new evidence for epigenetic mechanisms

Betaine attenuates hepatic steatosis by reducing methylation of the MTTP promoter and elevating genomic methylation in mice fed a high-fat diet