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Tag: metabolic enhancer

Preventing the return of fear using reconsolidation updating and methylene blue is differentially dependent on extinction learning

This animal study explored how reconsolidation updating, a behavioral technique, and methylene blue (MB), a metabolic enhancer, could prevent the return of conditioned fear responses in rats. Reconsolidation updating broadly reduced fear reinstatement, while MB was effective specifically in rats responsive to extinction learning. These findings suggest potential clinical strategies

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June 26, 2025 No Comments

Extinction memory improvement by the metabolic enhancer methylene blue

This animal study examined the effects of methylene blue (MB), a metabolic enhancer, on extinction memory retention in rats. Results showed that MB-treated rats exhibited significantly lower freezing behavior in response to the conditioned stimulus, indicating improved retention of extinction memory. Additionally, MB increased brain cytochrome oxidase activity by 38%,

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June 26, 2025 No Comments