Tag: metabolic diseases

Isolated remethylation disorders: do our treatments benefit patients?

This review article discusses isolated remethylation disorders, such as deficiencies in MTHFR and other rare defects like methionine synthase, which impair methionine synthesis and lead to elevated homocysteine levels. These disorders manifest with neurological and hematological symptoms and can lead to severe neurological deterioration or death without early intervention. Treatment

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Effects of alpha lipoic acid on metabolic syndrome: A comprehensive review

The meta-analysis titled “The effects of alpha-lipoic acid supplementation on glucose control and lipid profiles among patients with metabolic diseases: a systematic review and meta-analysis of randomized controlled trials” evaluated the impact of alpha-lipoic acid (ALA) supplementation on glucose homeostasis and lipid profiles in individuals with metabolic diseases. The analysis

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The effects of alpha-lipoic acid supplementation on glucose control and lipid profiles among patients with metabolic diseases: A systematic review and meta-analysis of randomized controlled trials

This systematic review and meta-analysis of 24 randomized controlled trials assessed the effects of alpha-lipoic acid (ALA) supplementation on glycemic control and lipid profiles in patients with metabolic diseases. ALA dosages ranged from 200 to 1,800 mg/day over 2 to 51 weeks. The analysis found significant improvements in fasting glucose

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