Well Referenced

Tag: mercury poisoning

Mercury binding to the chelation therapy agents DMSA and DMPS and the rational design of custom chelators for mercury

This study investigates the efficacy of two commonly used chelation therapy agents, meso-2,3-dimercaptosuccinic acid (DMSA) and 2,3-dimercaptopropane-1-sulfonic acid (DMPS), in binding mercuric ions (Hg²⁺). Using mercury L(III)-edge X-ray absorption spectroscopy and density functional theory calculations, researchers found that neither DMSA nor DMPS forms true chelate complexes with Hg²⁺, which may

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June 26, 2025 No Comments

Metal chelators and neurotoxicity: lead, mercury, and arsenic

This review examines the use of metal chelators, including DMSA, DMPS, and CaEDTA, in treating lead, mercury, and arsenic poisoning, with a focus on their efficacy, safety, and potential combination therapies. The study highlights that DMSA is a safer alternative to CaEDTA for moderate lead poisoning and suggests that DMSA

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June 26, 2025 No Comments

Mobilization of heavy metals by newer, therapeutically useful chelating agents

This review examines the effectiveness and safety of four chelating agents—DMSA, DMPS, CaNa₂EDTA, and BAL—for treating heavy metal poisoning, particularly lead, mercury, and arsenic intoxication. The study highlights that DMSA and DMPS are safer and more effective alternatives to traditional chelators like CaNa₂EDTA and BAL, with DMSA primarily used for

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June 26, 2025 No Comments