This 2019 randomized controlled trial evaluated the efficacy of combining intensive behavioral therapy (IBT) with liraglutide 3.0 mg, with or without a 12-week meal replacement diet, in 150 adults with obesity over 52 weeks. Participants were assigned to one of three groups: IBT alone, IBT plus liraglutide, or IBT plus
This 2008 randomized controlled trial by König et al. assessed the impact of a soy-based meal replacement regimen on metabolic risk factors in overweight and obese individuals over six weeks. Ninety participants were divided into two groups: one followed a fat-restricted low-calorie diet (LCD), and the other replaced two daily
This randomized controlled trial evaluated the effectiveness of meal replacements (MR) compared to a structured low-fat, low-calorie diet (C) in 66 overweight/obese Australian adults aged 20–65 with elevated triglycerides. Over two 3-month phases, both groups followed a 6000 kJ/day regimen. The MR group consumed two Slim-Fast products and a low-fat
