Well Referenced

Tag: MCP-1

Influence of yeast-derived 1,3/1,6 glucopolysaccharide on circulating cytokines and chemokines with respect to upper respiratory tract infections

This 2012 randomized, double-blind, placebo-controlled trial evaluated the effects of daily supplementation with 250 mg of Wellmune WGP®, a yeast-derived 1,3/1,6 β-glucan, over 90 days in 100 healthy adults during peak upper respiratory tract infection (URTI) season. Participants recorded daily health logs, and URTI symptoms triggered medical assessments and blood

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June 26, 2025 No Comments

Natural Compound Resveratrol Attenuates TNF-Alpha-Induced Vascular Dysfunction in Mice and Human Endothelial Cells: The Involvement of the NF-κB Signaling Pathway

This study explored how resveratrol, a natural polyphenol, protects against TNF-α-induced vascular inflammation in human endothelial cells and mice. At physiologically relevant concentrations (as low as 1 μM), resveratrol significantly reduced monocyte adhesion, lowered expression of key inflammatory markers like MCP-1/CCL2 and ICAM-1, and inhibited NF-κB pathway activation. In mice,

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June 26, 2025 No Comments