Vitamin D supplementation and major cardiovascular events: D-Health randomised controlled trial
This 2023 randomized, double-blind, placebo-controlled trial investigated whether monthly high-dose vitamin D supplementation (60,000 IU) reduces major cardiovascular events (MACE) in adults aged 60–84 years. Over a median follow-up of 5 years, the study found a 9% reduction in MACE incidence in the vitamin D group compared to placebo (hazard