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Tag: MACE

Testosterone Replacement Therapy and Cardiovascular Disease

This review examines the evolving evidence on the cardiovascular safety of testosterone replacement therapy (TRT) in men with hypogonadism. While earlier observational studies raised alarms over increased cardiovascular risks—including myocardial infarction and stroke—recent randomized trials, particularly the TRAVERSE study, provide reassurance that TRT does not significantly increase the risk of

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June 26, 2025 No Comments

Coronary Calcium Characteristics as Predictors of Major Adverse Cardiac Events in Symptomatic Patients: Insights From the CORE 320 Multinational Study

This 2019 analysis from the CORE 320 trial assessed 379 symptomatic patients aged 45–85 undergoing coronary artery calcium (CAC) scanning and CT angiography to evaluate the predictive value of different CAC metrics for major adverse cardiac events (MACE) over a two-year follow-up. Among the parameters studied—Agatston score, calcium volume, area,

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June 26, 2025 No Comments