Tag: lung function

Molecular and physiological manifestations and measurement of aging in humans

This 2017 review outlines the mechanisms of aging, emphasizing both molecular and physiological aspects. It discusses well-described molecular and cellular hallmarks and physiological changes of aging at the organ-system level. The authors propose methods to measure aging by integrating molecular biology (e.g., telomere length, epigenetic marks) and physiological function (e.g.,

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Blood fibrinogen as a biomarker of chronic obstructive pulmonary disease

This study published in Thorax explores the role of blood fibrinogen as a biomarker in chronic obstructive pulmonary disease (COPD). The review suggests that fibrinogen levels are significantly associated with COPD presence, exacerbation frequency, and mortality risk, making it a potential biomarker for risk stratification. However, fibrinogen does not predict

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Antioxidant supplementation for lung disease in cystic fibrosis

This systematic review evaluated the use of antioxidant supplementation—such as vitamins C and E, beta-carotene, selenium, glutathione, and N-acetylcysteine—in managing lung disease in individuals with cystic fibrosis (CF). While the review found a potential link between oxidative status and lung function, the evidence was limited by study variability, inconsistent outcomes,

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