This 2022 review examines the potential effects of COVID-19 on human reproductive health. It discusses how SARS-CoV-2 may impact gonadal function through ACE2 and TMPRSS2 expression in reproductive tissues, leading to possible tissue inflammation and dysfunction. In women, the pandemic has been associated with menstrual irregularities, reduced oocyte quality, and
This randomized controlled trial investigated the effects of major ozone autohemotherapy (O₃-MAH) on patients with post-acute sequelae of COVID-19 (PASC). Seventy-three patients were assigned to receive either O₃-MAH plus conventional therapy or conventional therapy alone. The O₃-MAH group showed significantly greater improvements in symptoms, pulmonary function, and inflammatory markers, particularly
This study explored the efficacy of oxygen-ozone autohemotherapy (O2-O3-AHT) for treating fatigue in patients suffering from post-acute sequelae of SARS-CoV2 (PASC), also known as long COVID. The trial involved 100 patients and found that O2-O3-AHT resulted in a 67% reduction in fatigue, with 40% of patients experiencing complete recovery. The
This systematic review examined the effectiveness and feasibility of high-dose intravenous (IV) vitamin C in treating fatigue, particularly in post-viral contexts such as long COVID. Across nine studies with 720 participants, three of four controlled trials and four of five observational studies showed a significant reduction in fatigue levels in
This systematic review analyzed ten clinical studies, including randomized controlled trials and observational studies, to evaluate the effects of hyperbaric oxygen therapy (HBOT) on long COVID symptoms. The findings suggest that HBOT may improve quality of life, fatigue, cognition, neuropsychiatric symptoms, and cardiopulmonary function in long COVID patients. However, the
This observational study investigated the effects of hyperbaric oxygen therapy (HBOT) on individuals suffering from long COVID symptoms, particularly fatigue and cognitive dysfunction. Ten participants received 10 HBOT sessions over 12 days, which led to significant improvements in fatigue, executive function, attention, information processing, and verbal function. While no adverse
