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Tag: Lipoic acid

Supplementation of Lipoic Acid, Zinc and Clopidogrel Reduces Mortality Rate and Incidence of Ventricular Arrhythmia in Experimental Myocardial Infarction

This 2021 animal study published in Frontiers in Physiology (DOI: 10.3389/fphys.2021.582223, PMCID: PMC8009994) evaluated the cardioprotective effects of lipoic acid, zinc, and clopidogrel in Wistar rats with isoproterenol-induced myocardial infarction (MI). The study found that pre-treatment with these agents reduced mortality rates, ventricular arrhythmias, ST-segment elevation, and CK-MB levels. Lipoic

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June 26, 2025 No Comments

Nutraceutical strategies for ameliorating the toxic effects of alcohol

This article discusses the use of nutraceuticals like spirulina, taurine, pantethine, and lipoic acid to reduce the toxic effects of alcohol, particularly by alleviating oxidative stress and promoting the breakdown of acetaldehyde. Spirulina inhibits NADPH oxidase, which reduces oxidative damage, while taurine, pantethine, and lipoic acid enhance the activity of

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June 26, 2025 No Comments

Role of lipoic acid in multiple sclerosis

The article titled “Role of lipoic acid in multiple sclerosis” (CNS Neuroscience & Therapeutics, 2022, PMID: 34964271) is a systematic review analyzing the pharmacokinetics, efficacy, safety, and mechanisms of lipoic acid (LA) in multiple sclerosis (MS). It reviews 20 studies on LA effects in cell and mouse models of MS

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June 26, 2025 No Comments