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Tag: Linaclotide

Chronic constipation: current treatment options

This 2011 review outlines the management strategies for chronic constipation, emphasizing a stepwise approach. Initial interventions include dietary and lifestyle modifications, such as increased fiber intake and physical activity. Pharmacologic treatments encompass bulking agents (e.g., psyllium), stool softeners, osmotic laxatives (e.g., polyethylene glycol), and stimulant laxatives (e.g., bisacodyl). The review

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June 26, 2025 No Comments

American Gastroenterological Association Institute Guideline on the Pharmacological Management of Irritable Bowel Syndrome

This 2014 guideline by the American Gastroenterological Association (AGA) provides evidence-based recommendations for the pharmacological treatment of irritable bowel syndrome (IBS) in adults. Utilizing the GRADE methodology, the guideline evaluates various medications for IBS subtypes. For IBS with constipation (IBS-C), it recommends linaclotide and lubiprostone. For IBS with diarrhea (IBS-D),

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June 26, 2025 No Comments