This 2006 review by Layman and Walker discusses the role of leucine, a branched-chain amino acid, in managing obesity and metabolic syndrome. The authors highlight that diets with protein intake >1.5 g/kg/day and carbohydrate intake
This narrative review examines the effects of isolated leucine and branched-chain amino acid (BCAA) supplementation on muscle strength and hypertrophy. The authors analyze various studies and conclude that while leucine and BCAAs play a role in muscle protein synthesis, supplementation alone does not significantly enhance muscular strength or hypertrophy beyond
The 2009 study “Glutamine, arginine, and leucine signaling in the intestine” (DOI: 10.1007/s00726-008-0225-4) investigates the roles of glutamine, arginine, and leucine in promoting intestinal health through various signaling pathways, including MAPK, mTOR, and cGMP. These amino acids stimulate cell migration, enhance mucosal integrity, and protect against oxidative stress and nutrient
