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Tag: Lequesne Index

Prospective clinical study on extracorporeal shock wave therapy combined with platelet-rich plasma injection for knee osteoarthritis

This 2019 prospective randomized clinical trial evaluated the efficacy of extracorporeal shock wave therapy (ESWT) combined with platelet-rich plasma (PRP) injections in 180 patients with knee osteoarthritis (KOA). Participants were divided into three groups: Group A received intra-articular PRP injections; Group B underwent ESWT; Group C received both treatments. All

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June 26, 2025 No Comments

The comparison effects of intra-articular injection of Platelet Rich Plasma (PRP), Plasma Rich in Growth Factor (PRGF), Hyaluronic Acid (HA), and ozone in knee osteoarthritis; a one year randomized clinical trial

This 2021 randomized clinical trial evaluated the short- and long-term efficacy of intra-articular injections of PRP, PRGF, HA, and ozone in 200 patients with mild to moderate knee osteoarthritis. Patients were randomized into four groups: PRP (2 doses, 3-week interval), PRGF (2 doses, 3-week interval), HA (3 weekly doses), and

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June 26, 2025 No Comments

Pharmaceutical-grade Chondroitin sulfate is as effective as celecoxib and superior to placebo in symptomatic knee osteoarthritis: the ChONdroitin versus CElecoxib versus Placebo Trial (CONCEPT)

This 2017 randomized, double-blind, placebo- and celecoxib-controlled trial evaluated the efficacy and safety of pharmaceutical-grade chondroitin sulfate (CS) 800 mg/day in 604 patients with symptomatic knee osteoarthritis over 6 months. CS demonstrated a statistically significant reduction in pain (−42.6 mm on VAS) and improvement in function (−4.7 on Lequesne Index)

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June 26, 2025 No Comments