Tag: learned helplessness

Selecting an Appropriate Animal Model of Depression

This comprehensive review evaluates various animal models used to study depression, emphasizing the importance of selecting appropriate models to elucidate the underlying mechanisms of the disorder. The authors discuss commonly used models such as the forced swim test, tail suspension test, chronic mild stress, learned helplessness, social defeat, and genetic

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Methylene blue facilitates the extinction of fear in an animal model of susceptibility to learned helplessness

This study examined the effects of methylene blue on the extinction of conditioned fear responses in rats predisposed to learned helplessness. The results demonstrated that methylene blue administration enhanced the extinction of fear, suggesting its potential role in influencing memory processes related to fear. This finding has implications for developing

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