This 2014 review by Avci et al. analyzed the efficacy of low-level laser therapy (LLLT) for treating hair loss, including androgenetic alopecia and alopecia areata. The review encompassed preclinical and clinical studies, showing that LLLT can stimulate hair regrowth in both animal models (e.g., chemotherapy-induced alopecia in mice) and humans.
A study published in Lasers in Medical Science (2019) investigated the effects of 808-nm diode laser photobiomodulation (PBM) on wound healing in human endothelial cells. The results showed that PBM increased the production of reactive oxygen species (ROS), which in turn stimulated mitochondrial oxidative phosphorylation, boosting ATP production and promoting
This review explores the clinical applications of photobiomodulation (PBM), or low-level light therapy (LLLT), in dermatology and regenerative medicine, highlighting its role in enhancing mitochondrial ATP production, modulating oxidative stress, and promoting cell signaling for tissue repair. PBM has shown potential in improving skin appearance, treating acne vulgaris, accelerating wound
This review article examined 30 studies to assess the effects of photobiomodulation (PBM) on mesenchymal stem cells (MSCs), highlighting its role in enhancing MSC proliferation. Effective PBM parameters included energy densities between 0.7 and 4 J/cm² and wavelengths in the 600-700 nm range. The findings suggest that PBM can positively
This in vivo study examined the effects of red and near-infrared wavelengths in low-level laser therapy (LLLT) on the healing of partial-thickness dermal abrasions in mice. The results showed that both red and near-infrared light significantly accelerated wound healing, enhancing re-epithelialization and collagen deposition compared to controls. These findings suggest
This pilot study evaluated the combined effects of fractional resurfacing and photodynamic therapy (PDT) with aminolevulinic acid (ALA) on perioral wrinkles in four female patients. After two sessions of fractional resurfacing with the Fraxel SR device, ALA-PDT was applied to one half of the perioral area, showing enhanced improvements in
