This 2015 prospective cohort study from the Japan Collaborative Cohort (JACC) study, published in the Journal of Clinical Nutrition, followed 58,615 adults aged 40–79 over a median of 14.7 years to examine the impact of dietary magnesium intake on mortality outcomes. Participants in the highest quintile of magnesium intake had
This 2008 prospective cohort study published in the American Journal of Epidemiology analyzed data from 58,615 Japanese adults in the Japan Public Health Center-based Study Cohort I to evaluate the association between dietary magnesium intake and stroke risk over an average follow-up of 10.7 years. Among men, higher magnesium intake
This study evaluated the bioenergetic role of coenzyme Q10 (CoQ10) in essential hypertension by measuring the specific activities of succinate dehydrogenase-CoQ10 reductase in 65 healthy Japanese adults and 59 hypertensive patients. Results showed significantly lower enzyme activity (p < 0.001) and higher deficiency in the hypertensive group compared to controls.
