This prospective observational study assessed the incidence and predictors of hair loss in 42 morbidly obese female patients undergoing laparoscopic sleeve gastrectomy (LSG). Over a 12-month postoperative period, 41% of patients reported hair loss. While mean serum zinc and iron levels remained within normal ranges, low levels of these micronutrients
This 2020 review explores the complex interplay between ascorbic acid (vitamin C) and iron, emphasizing their redox and chelation dynamics with significant clinical implications. Vitamin C enhances iron absorption by reducing ferric (Fe³⁺) to ferrous (Fe²⁺) iron, facilitating uptake. However, this reduction can also catalyze the Fenton reaction, generating reactive
This 2019 review by Kim et al. provides a comprehensive overview of heavy metal toxicity and the role of chelation therapy in its management. The authors discuss how heavy metals such as arsenic, cadmium, copper, iron, lead, and mercury can induce oxidative stress by generating free radicals and depleting antioxidant
This 2005 review by Liu et al. explores the potential of nanoparticle-conjugated chelators as a novel therapeutic strategy for Alzheimer’s disease (AD). Traditional chelation therapies, such as desferrioxamine, have shown limited efficacy due to poor blood-brain barrier (BBB) permeability and systemic side effects. The authors propose that nanoparticles conjugated to
This 2023 review examines the role of trace metal dyshomeostasis—particularly involving copper (Cu), zinc (Zn), and iron (Fe)—in Alzheimer’s disease (AD) pathogenesis. It highlights how abnormal accumulation of these metals contributes to amyloid-β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, and neuroinflammation. The study evaluates various chelating agents, such as deferoxamine,
This observational animal study investigated the effects of heated coriander (Coriandrum sativum) leaf extract on heavy metal accumulation and oxidative stress resistance in mice. After eight weeks of consuming water with 0.25% heated coriander extract, mice showed significantly reduced concentrations of iron, cadmium, and arsenic in the kidneys, but not
This 2014 review article explores the roles of essential elements—zinc, magnesium, lithium, iron, calcium, and chromium—in the development and treatment of depression and anxiety. It highlights evidence from preclinical and clinical studies linking deficiencies in these elements to mood disorders and notes that supplementation may improve the efficacy of antidepressants
The study examines the role of nutrition in thyroid disease management, focusing on the impact of essential micronutrients such as iodine, selenium, iron, zinc, and vitamins B12, D3, and A on thyroid function. It highlights the benefits of the Mediterranean diet in improving immune, endocrine, and biomolecular responses in thyroiditis
This systematic review examines the impact of vitamins and minerals on hair loss, emphasizing the importance of nutrients like iron, zinc, and vitamins A, B, C, D, and E. Deficiencies in these micronutrients can contribute to alopecia, and correcting them may help prevent or treat hair loss. The review suggests
