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Tag: intestinal barrier function

Glutamine and intestinal barrier function

The 2014 article titled “Glutamine and intestinal barrier function” (PMID: 24965526) reviews the vital role of glutamine in maintaining intestinal barrier integrity. Glutamine is shown to promote enterocyte proliferation, regulate the expression and assembly of tight junction proteins, and support overall mucosal health. These functions are particularly critical under stress

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June 26, 2025 No Comments

Glutamine Restores Tight Junction Protein Claudin-1 Expression in Colonic Mucosa of Patients With Diarrhea-Predominant Irritable Bowel Syndrome

The 2016 observational study titled “Glutamine Restores Tight Junction Protein Claudin-1 Expression in Colonic Mucosa of Patients With Diarrhea-Predominant Irritable Bowel Syndrome” (PMID: 25972430) examined the effect of glutamine on tight junction protein expression in IBS-D patients. Using colonic biopsy specimens from 12 patients, researchers incubated tissues with glutamine at

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June 26, 2025 No Comments