This 2020 retrospective study evaluated 8,606 intravenous (IV) push thiamine administrations in 2,595 adult patients at a tertiary academic medical center. Doses ranged from 100 mg to 500 mg, with the majority administered peripherally. The study found no instances of anaphylaxis or anaphylactoid reactions. Injection site reactions were rare, occurring
This 52-week, multinational, randomized, open-label, non-inferiority trial compared the efficacy and safety of insulin detemir and insulin glargine as add-on therapy to oral glucose-lowering drugs in insulin-naive adults with type 2 diabetes. A total of 582 participants were randomized to receive either insulin detemir or insulin glargine once daily, titrated
This systematic review (Forschende Komplementärmedizin, 2009, PMID: 19729932) evaluated 18 clinical trials involving over 6,800 patients to assess the efficacy and safety of standardized mistletoe (Viscum album) preparations as complementary cancer therapy. While the quality of the included studies was generally low and too heterogeneous for meta-analysis, the findings consistently
