Testosterone replacement therapy improves insulin resistance, glycaemic control, visceral adiposity and hypercholesterolaemia in hypogonadal men with type 2 diabetes
This randomized controlled trial examined the effects of testosterone replacement therapy (TRT) on metabolic parameters in hypogonadal men with type 2 diabetes mellitus (T2DM). The study found that TRT significantly improved insulin sensitivity, reduced HbA1c levels, decreased visceral adiposity, and enhanced lipid profiles, including reductions in total cholesterol and LDL