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Tag: human study

The Effects of Thyroid Hormones on Brown Adipose Tissue in Humans: A PET-CT Study

This 2014 clinical investigation explored how thyroid hormones influence brown adipose tissue (BAT) activity in euthyroid human subjects using PET-CT imaging. Participants with higher circulating thyroid hormone levels, especially triiodothyronine (T3), demonstrated significantly increased glucose uptake in BAT, indicating heightened thermogenic activity. The study confirmed that thyroid hormones directly stimulate

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June 26, 2025 No Comments

Nicotinamide riboside is uniquely and orally bioavailable in mice and humans

This 2016 study evaluated the pharmacokinetics and bioavailability of nicotinamide riboside (NR), a vitamin B3 derivative, in both mice and humans. In mice, oral NR administration led to significant increases in hepatic NAD⁺ levels, outperforming other NAD⁺ precursors like nicotinic acid and nicotinamide. In a human pilot study, a single

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June 26, 2025 No Comments