This 2015 study from the Study of Women’s Health Across the Nation (SWAN) evaluated the duration of frequent vasomotor symptoms (VMS), such as hot flashes and night sweats, in 1,449 women. The median duration of frequent VMS was 7.4 years overall, with symptoms persisting for a median of 4.5 years
This systematic review analyzed 10 double-blind, randomized, placebo-controlled trials to assess the efficacy of various ginseng preparations, including Korean Red Ginseng (KRG) and American ginseng, in managing menopausal symptoms. The findings indicated that ginseng may positively influence sexual function and reduce total hot flash scores, particularly with KRG. However, the
This randomized controlled trial compared radical prostatectomy (RP) with watchful waiting (WW) in 695 men with early prostate cancer over a median follow-up of 12 years, assessing symptom burden, androgen deprivation therapy (ADT) use, and quality of life (QoL). RP was associated with lower prostate cancer-specific mortality but higher rates
This study surveyed 469 breast cancer survivors to assess the severity of menopausal symptoms and their willingness to consider hormone replacement therapy (HRT). Over 76% reported experiencing hot flushes or night sweats, with 53% rating them as severe to extreme, significantly impacting their quality of life. Among those who had
This review article explores the role of estrogen and hormone replacement therapy (ERT/HRT) in managing menopausal symptoms and improving quality of life in women. It discusses how estrogen deficiency during menopause leads to symptoms such as hot flashes, sleep disturbances, sexual dysfunction, and mood changes. The review highlights growing evidence
This review addresses the management of menopausal symptoms in breast cancer survivors, focusing on the challenges of treating symptoms such as hot flashes, vaginal dryness, and osteoporosis without the use of traditional hormone replacement therapy (HRT), which is contraindicated due to its association with increased breast cancer recurrence. The article
This study examined the prevalence and severity of menopausal symptoms in breast cancer survivors, finding that nearly all participants reported vasomotor symptoms, with hot flashes being the most common. The severity of symptoms negatively impacted the women’s perceived quality of life, as well as their partners’. Despite the widespread issue,
This article reviews hormone therapy (HT) and other treatments for menopausal symptoms, emphasizing the risks and benefits of estrogen therapy for hot flashes and vaginal dryness. It discusses the use of combined estrogen/progestogen therapy, which increases breast cancer risk after prolonged use, recommending the lowest effective dose for the shortest
The article “Acute consequences of the menopausal transition: the rise of common menopausal symptoms” by Clarisa R. Gracia and Ellen W. Freeman, published in Endocrinology and Metabolism Clinics of North America (PMID: 15501640), reviews the onset and prevalence of menopausal symptoms such as hot flashes, night sweats, and mood changes,
A 2016 systematic review published in The Cochrane Database of Systematic Reviews (PMID: 27479272) evaluated the efficacy and safety of bioidentical hormone therapy (BHT) for menopausal vasomotor symptoms. Analyzing randomized controlled trials comparing BHT to placebo or conventional hormone therapy, the study found that 17β-estradiol effectively reduced the frequency and
