Well Referenced

Tag: hormonal changes

Pathways from Dieting to Weight Regain, to Obesity and to the Metabolic Syndrome: An Overview

This review examines the paradoxical outcomes of dieting, highlighting that a significant proportion of individuals regain lost weight within five years, with some surpassing their initial weight. The authors explore mechanisms such as metabolic adaptations, hormonal changes, and behavioral factors contributing to weight regain. The phenomenon of “catch-up fat” is

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June 26, 2025 No Comments

The endocrine system and ageing

The article “The endocrine system and ageing” discusses the hormonal changes that occur with aging, including declines in estrogen, testosterone, growth hormone, and other key hormones, as well as increases in certain others like luteinizing hormone and sex hormone-binding globulin. These alterations contribute to various clinical consequences such as reduced

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June 26, 2025 No Comments

The menopause and sexual functioning: a review of the population-based studies

This systematic review examines population-based studies assessing the impact of menopause on women’s sexual functioning, distinguishing between age-related and menopause-specific declines. Findings indicate that sexual dysfunction increases with menopausal transition, as seen in the Melbourne Women’s Midlife Health Project, where rates rose from 42% in early menopause to 88% in

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June 26, 2025 No Comments

Spotlight on the Gut Microbiome in Menopause: Current Insights

This observational study explores the impact of menopause on gut microbiome composition and diversity, highlighting how declining estrogen and progesterone levels lead to reduced microbial diversity and shifts in bacterial populations. Post-menopausal women exhibit lower levels of beneficial bacteria (e.g., Firmicutes, Ruminococcus) and increased potentially harmful bacteria (e.g., Prevotella, Bilophila),

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June 26, 2025 No Comments

Hormones and menopausal status as predictors of depression in women in transition to menopause

This cohort study investigates the relationship between hormonal fluctuations during the transition to menopause and depressive symptoms in women aged 35-47. The results showed that depressive symptoms increased during the transition to menopause and decreased after menopause, with hormonal markers such as follicle-stimulating hormone (FSH) and estradiol being significant factors

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June 26, 2025 No Comments