Well Referenced

Tag: HOMA-IR

Dietary Supplementation with Inulin Modulates the Gut Microbiota and Improves Insulin Sensitivity in Prediabetes

This 2021 observational study published in the International Journal of Endocrinology (PMID: 34257649) investigated the effects of inulin supplementation on insulin sensitivity and gut microbiota in individuals with prediabetes. Over six months, 49 participants consumed 15 g of inulin daily, resulting in significant improvements in insulin sensitivity, with reductions in

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June 26, 2025 No Comments

An updated systematic review and dose-response meta-analysis of the effects of α-lipoic acid supplementation on glycemic markers in adults

The systematic review and dose-response meta-analysis titled “An updated systematic review and dose-response meta-analysis of the effects of α-lipoic acid supplementation on glycemic markers in adults” investigated the impact of α-lipoic acid (ALA) supplementation on glycemic markers, including glucose, hemoglobin A1c (HbA1c), insulin, and insulin resistance indices in adults. The

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June 26, 2025 No Comments

Testosterone therapy reduces insulin resistance in men with adult-onset testosterone deficiency and metabolic syndrome. Results from the Moscow Study, a randomized controlled trial with an open-label phase

Testosterone therapy was found to significantly reduce insulin resistance in men with metabolic syndrome (MetS) and hypogonadism, particularly in those not receiving antiglycaemic therapy. The study, a randomized controlled trial, included 184 men, with 113 receiving testosterone undecanoate (TU) and 71 receiving placebo. Results showed a significant reduction in HOMA-IR,

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June 26, 2025 No Comments

Essentials of female sexual dysfunction from a sex therapy perspective

In this randomized controlled trial published in the Journal of Clinical Endocrinology & Metabolism in 2007 (PMID: 17390929), 100 hypogonadal men with type 2 diabetes aged 40–70 were randomized to receive either intramuscular testosterone enanthate (200 mg every two weeks) or placebo for 6 months to evaluate its effects on

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June 26, 2025 No Comments