Ocimum tenuiflorum extract (HOLIXERTM): Possible effects on hypothalamic-pituitary-adrenal (HPA) axis in modulating stress
This study evaluated the anti-stress effects of Holixer™, a standardized extract of Ocimum tenuiflorum (Holy Basil), using in vivo models (swim endurance in mice and forced swim tests in rats) and in vitro HPA-axis assays. Results showed that Holixer™ significantly improved physical endurance, reduced stress-induced immobility, and normalized corticosterone levels.
June 26, 2025
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