Well Referenced

Tag: high-fat diet

Metabolaid® Combination of Lemon Verbena and Hibiscus Flower Extract Prevents High-Fat Diet-Induced Obesity through AMP-Activated Protein Kinase Activation

This 2018 preclinical study investigated the effects of Metabolaid®, a combination of lemon verbena and hibiscus flower extracts, on obesity and metabolic parameters in high-fat diet-induced obese mice. The treatment led to significant reductions in body weight, white adipose tissue, and liver weight. Improvements were observed in serum and hepatic

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June 26, 2025 No Comments

Betaine attenuates hepatic steatosis by reducing methylation of the MTTP promoter and elevating genomic methylation in mice fed a high-fat diet

This study examined the effects of betaine supplementation on hepatic steatosis in mice fed a high-fat diet, with a focus on epigenetic mechanisms. Betaine was found to improve liver function by reducing methylation of the microsomal triglyceride transfer protein (MTTP) promoter, leading to increased MTTP expression, which plays a crucial

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June 26, 2025 No Comments

Effect of Dehydroepiandrosterone (DHEA) on Diabetes Mellitus and Obesity

The article “Effects of dehydroepiandrosterone (DHEA) on diabetes mellitus and obesity” examines DHEA’s impact on insulin secretion and sensitivity. In animal models, DHEA improved insulin signaling by enhancing pancreatic insulin secretion, reducing hepatic gluconeogenesis, and increasing Akt phosphorylation in the liver of insulin receptor substrate-deficient mice on a high-fat diet.

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June 26, 2025 No Comments