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Tag: high-dose ascorbate

Vitamin C Administration by Intravenous Infusion Increases Tumor Ascorbate Content in Patients With Colon Cancer: A Clinical Intervention Study

This 2021 clinical intervention study assessed the effects of high-dose intravenous vitamin C on tumor ascorbate levels in patients with colon cancer. Participants received up to 1 g/kg/day of ascorbate for four days before tumor resection. The intervention significantly increased ascorbate concentrations in plasma, erythrocytes, and tumor tissues, with tumor

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June 26, 2025 No Comments

Intravenous Vitamin C for Cancer Therapy – Identifying the Current Gaps in Our Knowledge

This 2018 review critically examines the use of high-dose intravenous vitamin C (IVC) in cancer therapy, highlighting the lack of standardized clinical protocols and definitive evidence. It addresses key questions regarding IVC’s safety, optimal dosing, interaction with conventional treatments, and mechanisms of action, such as pro-oxidant effects leading to hydrogen

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June 26, 2025 No Comments

Intravenously Administered Vitamin C as Cancer Therapy: Three Cases

This 2006 case series evaluated three patients with advanced cancers who received high-dose intravenous vitamin C (IVC) therapy. Each patient experienced unexpectedly prolonged survival and clinical improvement. Pharmacokinetic data indicated that IVC achieves plasma concentrations (~14,000 μmol/L) significantly higher than oral administration, levels at which vitamin C exhibits selective cytotoxicity

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June 26, 2025 No Comments