Well Referenced

Tag: hemolytic anemia

Membrane lipid composition of red blood cells in liver disease: regression of spur cell anaemia after infusion of polyunsaturated phosphatidylcholine

This 1978 study investigated the effects of polyunsaturated phosphatidylcholine (PPC) infusion on red blood cell (RBC) membrane composition in patients with liver cirrhosis exhibiting spur cell anemia. Eight patients received 2 g/day of PPC for five days. Post-infusion results showed a decrease in the cholesterol-to-phospholipid molar ratio in RBC membranes

Read More »
June 26, 2025 No Comments

Acquired Glucose-6-Phosphate Dehydrogenase Deficiency

This 2022 narrative review explores the phenomenon of acquired G6PD deficiency, a condition where G6PD enzyme activity is reduced due to non-genetic factors. Unlike the hereditary form, acquired G6PD deficiency arises from biochemical mechanisms that inhibit the enzyme in specific clinical contexts. The review identifies conditions such as hyperaldosteronism, diabetes,

Read More »
June 26, 2025 No Comments

Inborn errors in the metabolism of glutathione

This review discusses rare inherited disorders affecting the metabolism of glutathione, a key antioxidant involved in detoxification, redox regulation, and cellular protection. These inborn errors occur in five of the six enzymes of the gamma-glutamyl cycle and include glutathione synthetase deficiency (the most common), gamma-glutamylcysteine synthetase deficiency, gamma-glutamyl transpeptidase deficiency,

Read More »
June 26, 2025 No Comments