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Tag: Hematopoietic Stem Cell Transplantation

Natural Killer Cell Deficiency

This comprehensive review discusses Natural Killer Cell Deficiency (NKD), a rare primary immunodeficiency characterized by absent or dysfunctional NK cells, leading to increased susceptibility to viral infections and certain cancers. NKD is classified into classical NKD (cNKD), marked by a significant reduction or absence of NK cells, and functional NKD

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June 26, 2025 No Comments

The potential role of the thymus in immunotherapies for acute myeloid leukemia

This 2023 review explores the significance of the thymus in shaping T-lymphocyte immunity and its implications for immunotherapeutic strategies in acute myeloid leukemia (AML). The thymus is crucial for generating a diverse T-cell repertoire during early life, but its function declines with age and disease, leading to impaired T-cell-mediated immunity.

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June 26, 2025 No Comments