This 1977 double-blind, placebo-controlled trial evaluated the efficacy of HCG injections in treating obesity. Participants received either HCG or placebo injections while adhering to a low-calorie diet. The study found no significant differences between the HCG and placebo groups in terms of weight loss, hunger levels, mood changes, or localized
This retrospective study analyzed 223 azoospermic men with congenital hypogonadotropic hypogonadism (CHH) treated with combined human chorionic gonadotropin (hCG) and human menopausal gonadotropin (hMG) over a median follow-up of 15 months. Results showed that 64% of patients achieved spermatogenesis, with a median time to sperm appearance of 15 months. Significant
This 2015 review addresses the challenge of managing hypogonadism in men desiring fertility preservation. Exogenous testosterone therapy can suppress the hypothalamic-pituitary-gonadal axis, leading to impaired spermatogenesis and potential azoospermia. The authors highlight alternative treatments, such as human chorionic gonadotropin (hCG), which can stimulate endogenous testosterone production and maintain intratesticular testosterone
