This prospective observational study assessed the incidence and predictors of hair loss in 42 morbidly obese female patients undergoing laparoscopic sleeve gastrectomy (LSG). Over a 12-month postoperative period, 41% of patients reported hair loss. While mean serum zinc and iron levels remained within normal ranges, low levels of these micronutrients
This 2006 review by Dr. Ralph M. Trüeb addresses the biological and environmental contributors to hair aging, including genetic factors, hormonal changes, oxidative stress, and UV radiation. The article outlines established pharmacologic treatments such as topical minoxidil and oral finasteride, which are effective for androgenetic alopecia and age-related hair thinning.
This 2014 review by Avci et al. analyzed the efficacy of low-level laser therapy (LLLT) for treating hair loss, including androgenetic alopecia and alopecia areata. The review encompassed preclinical and clinical studies, showing that LLLT can stimulate hair regrowth in both animal models (e.g., chemotherapy-induced alopecia in mice) and humans.
This 2018 randomized controlled trial published in the Journal of the European Academy of Dermatology and Venereology (PMID: 29972712) compared the effectiveness and safety of a topical solution combining 0.25% finasteride with 3% minoxidil versus 3% minoxidil alone in men with androgenetic alopecia (AGA). Over 24 weeks, the combination therapy
This systematic review explores the multifaceted causes and treatments of androgenetic alopecia (AGA), emphasizing the importance of early and continuous therapy. It highlights the FDA-approved treatments—topical minoxidil and oral finasteride—while discussing additional therapeutic options targeting androgen activity, inflammation, prostaglandins, and genetic predisposition. The review encourages a personalized, combination-based approach for
This review article on Iron Deficiency Anemia (IDA) outlines its widespread prevalence, particularly due to menstrual blood loss and gastrointestinal bleeding. It emphasizes that iron deficiency impacts more than hemoglobin levels, leading to symptoms like fatigue, hair loss, and restless legs syndrome. Serum ferritin is identified as the most accurate
This systematic review evaluated the efficacy of biotin supplementation for hair and nail growth, analyzing 18 case reports involving patients with conditions such as biotinidase deficiency, uncombable hair syndrome, and brittle nail syndrome. All cases showed clinical improvement with biotin supplementation, but there is no strong evidence supporting its routine
This study investigates the effects of D-panthenol (Vitamin B5) on human hair follicle cells, showing that it promotes cell growth by enhancing cell viability, reducing apoptosis and senescence, and upregulating hair growth factors like VEGF. The findings suggest its potential use in treating hair loss and stimulating hair growth. However,
This systematic review examines the impact of vitamins and minerals on hair loss, emphasizing the importance of nutrients like iron, zinc, and vitamins A, B, C, D, and E. Deficiencies in these micronutrients can contribute to alopecia, and correcting them may help prevent or treat hair loss. The review suggests
