Tag: Hair Loss Treatment

Topical Minoxidil Fortified with Finasteride: An Account of Maintenance of Hair Density After Replacing Oral Finasteride

This 2015 retrospective study evaluated the maintenance of hair density in 50 male patients with androgenetic alopecia (AGA) who transitioned from oral finasteride to a topical formulation containing 5% minoxidil and 0.1% finasteride. After two years of oral finasteride and minoxidil therapy, patients switched to the topical regimen. Results showed

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The Efficacy and Use of Finasteride in Women: A Systematic Review

This 2019 systematic review evaluated the use of finasteride in women for treating hair disorders such as female pattern hair loss (FPHL), frontal fibrosing alopecia (FFA), and lichen planopilaris. It included various study designs—mainly observational—with treatment doses ranging from 0.5 mg to 5 mg daily and durations spanning 6 to

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Prospective randomized study of sexual function in men taking dutasteride for the treatment of androgenetic alopecia

This 2018 randomized controlled trial evaluated sexual adverse events in 117 men aged 23–50 receiving dutasteride 0.5 mg daily for androgenetic alopecia. During the 24-week double-blind phase, sexual adverse events (impotence, decreased libido, ejaculation disorders) occurred in 16% of the dutasteride group versus 8% in the placebo group. In the

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Lasers, lights, and compounds for hair loss in aesthetics

This 2022 review article from Clinical Dermatology (DOI: 10.1016/j.clindermatol.2021.08.013, PMID: 35190067) evaluates current and emerging treatments for hair loss, including topical agents (e.g., finasteride, spironolactone), oral minoxidil, nutraceuticals, platelet-rich plasma (PRP), low-level laser therapy (LLLT), fractional lasers, and laser-assisted drug delivery. The review underscores a multimodal approach, suggesting that combining

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Characteristics of Men Who Report Persistent Sexual Symptoms After Finasteride Use for Hair Loss

This 2016 observational study published in the Journal of Clinical Endocrinology & Metabolism (PMID: 27662439) evaluated men who reported persistent sexual symptoms after discontinuing finasteride for androgenetic alopecia. The study found no evidence of ongoing androgen deficiency or 5α-reductase inhibition, but symptomatic users displayed depressed mood and functional MRI changes

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A review of the treatment of male pattern hair loss

This 2020 review article from Expert Opinion on Pharmacotherapy (DOI: 10.1080/14656566.2020.1721463, PMID: 32066284) explores the pathogenesis and treatment options for male pattern hair loss (MPHL), or androgenetic alopecia. It highlights that early intervention with finasteride (a 5-alpha-reductase inhibitor) and minoxidil can slow progression and promote partial regrowth, though outcomes are

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Efficacy and safety of topical finasteride spray solution for male androgenetic alopecia: a phase III, randomized, controlled clinical trial

This 2022 phase III randomized, double-blind study (PMID: 34634163) evaluated topical finasteride spray versus placebo and oral finasteride in 458 men with androgenetic alopecia over 24 weeks. Topical finasteride significantly increased hair count compared to placebo (20.2 vs. 6.7 hairs; p < 0.001) and performed comparably to oral finasteride in

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