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Tag: glioblastoma multiforme

The Use of Intravenous Vitamin C as a Supportive Therapy for a Patient with Glioblastoma Multiforme

This case report documents the extended survival of a female patient with glioblastoma multiforme (GBM), who lived over four years following diagnosis—far surpassing the typical median survival of around 12 months. Standard care included surgical resection, radiation, and temozolomide chemotherapy, alongside adjunctive high-dose intravenous vitamin C (IVC) therapy administered two

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June 26, 2025 No Comments

Rising Incidence of Glioblastoma Multiforme in a Well-Defined Population

This 2020 epidemiological study analyzed glioblastoma multiforme (GBM) cases in Malta from 2008 to 2017. The incidence of GBM increased significantly from 0.73 to 4.49 per 100,000 people over the decade (p ≤ 0.001). Factors contributing to this rise may include an aging population, improved diagnostic techniques, and environmental exposures.

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June 26, 2025 No Comments

Exploring the cytotoxicity and anticancer effects of doxycycline and azithromycin on human glioblastoma multiforme cells

This study evaluated the cytotoxic and anticancer effects of doxycycline (DOXY) and azithromycin (AZI) on human glioblastoma multiforme (GBM) U87 cells. Using MTT, Hoechst, Annexin V-FITC/PI, and clonogenic assays, both antibiotics individually reduced cell viability in a dose- and time-dependent manner, comparable to temozolomide (TMZ). However, their combination exhibited antagonistic

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June 26, 2025 No Comments