Tag: GHRH1-29NH2

GH responses to intravenous bolus infusions of GH-releasing hormone and GH-releasing peptide-2 separately and in combination in adult volunteers

This randomized controlled trial evaluated the effects of intravenous administration of growth hormone-releasing hormone (GHRH1-29NH2) and growth hormone-releasing peptide-2 (GHRP-2), individually and combined, on growth hormone (GH) secretion in healthy adult males. GHRP-2 alone significantly increased GH secretion (AUC: 6205.1 ± 3216.9 mU/l·min) compared to GHRH alone (AUC: 2061.2 ±

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Growth hormone (GH)-releasing effects of synthetic peptide GH-releasing peptide-2 and GH-releasing hormone (1-29)NH2 in children with GH insufficiency and idiopathic short stature

This randomized controlled trial investigated the effects of GHRH1-29NH2 and GHRP-2, both individually and in combination, on growth hormone (GH) release in children with growth hormone insufficiency and idiopathic short stature. The results indicated that while both peptides effectively stimulated GH secretion, the combination of GHRH1-29NH2 and GHRP-2 had a

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Low-dose growth hormone-releasing hormone tests: a dose-response study

This clinical trial evaluated the dose-response relationship of GHRH(1-29)NH2 in stimulating growth hormone (GH) secretion in healthy adult males. The study found that both 10- and 100-microgram doses of GHRH(1-29)NH2 resulted in significant GH responses, with the 10-microgram dose eliciting a slower decline in GH levels, suggesting a more prolonged

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