Tag: gemcitabine

Role of Gemcitabine and Cisplatin as Neoadjuvant Chemotherapy in Muscle Invasive Bladder Cancer: Experience Over the Last Decade

This 2019 systematic review evaluated 13 studies involving 754 patients with muscle-invasive bladder cancer (MIBC) who received neoadjuvant chemotherapy with gemcitabine and cisplatin (GC) prior to radical cystectomy. The analysis demonstrated a complete pathological response (pT0) in 30% of patients and pathological downstaging to non–muscle-invasive disease (

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A Retrospective Study of Gemcitabine and Carboplatin With or Without Intravenous Vitamin C on Patients With Advanced Triple-Negative Breast Cancer

This retrospective study examines the effectiveness of combining gemcitabine and carboplatin chemotherapy with or without intravenous vitamin C in patients with advanced triple-negative breast cancer (TNBC). The results suggest that adding vitamin C to chemotherapy may improve treatment outcomes, with patients showing enhanced response rates and potentially reduced side effects.

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NCCAM/NCI Phase 1 Study of Mistletoe Extract and Gemcitabine in Patients With Advanced Solid Tumors

This 2013 Phase I trial (Evidence-Based Complementary and Alternative Medicine, PMID: 24285980) evaluated the safety, tolerability, and immunological effects of combining mistletoe extract (Viscum album) with gemcitabine chemotherapy in 44 patients with advanced solid tumors. The combination was well tolerated up to a maximum tolerated dose of gemcitabine 1380 mg/m²

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