Tag: gelatin nanoparticles

Curcumin-Loaded Gelatin Nanoparticles Cross the Blood-Brain Barrier to Treat Ischemic Stroke by Attenuating Oxidative Stress and Neuroinflammation

This study investigated the use of curcumin-loaded gelatin nanoparticles (Cur@GAR NPs) functionalized with rabies virus glycoprotein (RVG29) to enhance brain-targeted therapy for ischemic stroke. In vitro, these nanoparticles demonstrated improved solubility, stability, antioxidant, and antimicrobial properties, while in vivo experiments using a rat model of middle cerebral artery occlusion (MCAO)

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Discovery that a melanocortin regulates sexual functions in male and female humans

This study investigated the use of curcumin-loaded gelatin nanoparticles (Cur@GAR NPs) functionalized with rabies virus glycoprotein (RVG29) to enhance brain-targeted therapy for ischemic stroke. In vitro, these nanoparticles improved curcumin’s solubility, stability, antioxidant, and antimicrobial properties. In vivo studies using a middle cerebral artery occlusion (MCAO) rat model demonstrated that

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